The Role Of Neurovascular Unit In Neurodegeneration
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The Role Of Neurovascular Unit In Neurodegeneration
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Author : Dennis Qing Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-05
The Role Of Neurovascular Unit In Neurodegeneration written by Dennis Qing Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-05 with Science categories.
Cyclin Dependent Kinase 5 Cdk5
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Author : Nancy Y. Ip
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-02-28
Cyclin Dependent Kinase 5 Cdk5 written by Nancy Y. Ip and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-28 with Medical categories.
Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during both developmental stages and in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may serve as therapeutic treatment for a number of neurodegenerative diseases.
Common Pathways Linking Neurodegenerative Diseases The Role Of Inflammation
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Author : Grzegorz Kreiner
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-01
Common Pathways Linking Neurodegenerative Diseases The Role Of Inflammation written by Grzegorz Kreiner and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-01 with Science categories.
Neurodegenerative Diseases
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Author : Raymond Chuen-Chung Chang
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-12-09
Neurodegenerative Diseases written by Raymond Chuen-Chung Chang and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-09 with Medical categories.
Neurodegenerative Diseases - Processes, Prevention, Protection and Monitoring focuses on biological mechanisms, prevention, neuroprotection and even monitoring of disease progression. This book emphasizes the general biological processes of neurodegeneration in different neurodegenerative diseases. Although the primary etiology for different neurodegenerative diseases is different, there is a high level of similarity in the disease processes. The first three sections introduce how toxic proteins, intracellular calcium and oxidative stress affect different biological signaling pathways or molecular machineries to inform neurons to undergo degeneration. A section discusses how neighboring glial cells modulate or promote neurodegeneration. In the next section an evaluation is given of how hormonal and metabolic control modulate disease progression, which is followed by a section exploring some preventive methods using natural products and new pharmacological targets. We also explore how medical devices facilitate patient monitoring. This book is suitable for different readers: college students can use it as a textbook; researchers in academic institutions and pharmaceutical companies can take it as updated research information; health care professionals can take it as a reference book, even patients' families, relatives and friends can take it as a good basis to understand neurodegenerative diseases.
Understanding The Roles Of Glia And Circulating Leukocytes In Neurodegenerative Diseases
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Author : Tuan Leng Tay
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-03
Understanding The Roles Of Glia And Circulating Leukocytes In Neurodegenerative Diseases written by Tuan Leng Tay and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-03 with Medical categories.
Essential Guide To Neurodegenerative Disorders
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Author : Wael Mohamed
language : en
Publisher: Elsevier
Release Date : 2024-11-24
Essential Guide To Neurodegenerative Disorders written by Wael Mohamed and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-24 with Medical categories.
Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington's disease, Parkinson's disease, Friedreich' s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches. - Reviews big data and neurodegeneration disorders, including gene mapping - Examines the structural basis of protein assembly into amyloid filaments in neurodegenerative disease - Covers the progress and challenges of pharmacotherapy of neurodegenerative disorders
Advances In Understanding The Pathogenetic Mechanisms Of Neurodevelopmental Disorders And Neurodegenerative Disease The Environment As A Putative Risk Factor
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Author : Anna Maria Lavezzi
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-05
Advances In Understanding The Pathogenetic Mechanisms Of Neurodevelopmental Disorders And Neurodegenerative Disease The Environment As A Putative Risk Factor written by Anna Maria Lavezzi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-05 with Medical categories.
Neurodevelopmental disorders are generally influenced by genetic as well as intrauterine and extrauterine factors that affect the fetal-maternal environment and/or brain development that continues after birth. Specific genetic polymorphisms may increase susceptibility to environmental factors that alter the trajectory of brain development via diverse molecular mechanisms. In particular, the pre- and post-natal exposure to neurotoxic metals, pesticides, persistent organic pollutants, and other chemicals is increasingly recognized as involved in the pathogenesis of neurodevelopmental disorders, such as autism, deficiency attention/hyperactivity disorders, neurodegenerative disorders such as Parkinson's and Alzheimer's disease, chronic multiple sclerosis, and even fetal and infant death, including SIUDS (Sudden Unexplained Intrauterine Death Syndrome) and SIDS (Sudden Infant Death Syndrome).
Exploring Molecular Targets To Treat Neurodegenerative Disorders
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Author : Prashant Tiwari
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2024-05-01
Exploring Molecular Targets To Treat Neurodegenerative Disorders written by Prashant Tiwari and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-01 with Medical categories.
This book delves into the delicate realm of neurodegenerative illnesses, navigating the vast landscape of molecular targets with care and purpose. Researchers are studying the complex pathways involved in diseases such as Alzheimer’s, Parkinson’s, and Huntington’s in order to identify specific molecules that could be targeted for therapy. The present work explores potential methods of intervention by carefully analysing neural circuits, protein misfolding, and genetic predispositions, unravelling the complexities of the human mind by focusing on individual molecular targets. As new findings emerge, reducing the severe consequences of neurodegenerative illnesses becomes increasingly possible, providing optimism for millions of people throughout the world.
Cerebral Small Vessel Disease
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Author : Leonardo Pantoni
language : en
Publisher: Cambridge University Press
Release Date : 2014-05
Cerebral Small Vessel Disease written by Leonardo Pantoni and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05 with Medical categories.
Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
Fundamentals Of Neurodegeneration And Protein Misfolding Disorders
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Author : Martin Beckerman
language : en
Publisher: Springer
Release Date : 2015-11-06
Fundamentals Of Neurodegeneration And Protein Misfolding Disorders written by Martin Beckerman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-06 with Medical categories.
This unique text introduces students and researchers to the world of misfolded proteins, toxic oligomers, and amyloid assemblages, and the diseases of the brain that result. During the past few years the connections between failures in protein quality control and neurological disorders have been reinforced and strengthened by discoveries on multiple fronts. These findings provide novel insights on how amyloidogenic oligomers and fibrils form, interconvert from one state to another, and propagate from cell to cell and region to region. Starting with protein folding and protein quality control basics, the reader will learn how misfolded proteins can cause diseases ranging from prion diseases to Alzheimer’s disease and Parkinson’s disease to Huntington’s disease, amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Authoritative but written in a clear and engaging style, Fundamentals of Neurodegeneration and Protein Misfolding Disorders addresses one of today’s forefront areas of science and medicine. The text emphasizes the new groundbreaking biophysical and biochemical methods that enable molecular-level explorations and the conceptual breakthroughs that result. It contains separate chapters on each of the major disease classes. Special emphasis is placed on those factors and themes that are common to the diseases, especially failures in synaptic transmission, mitochondrial control, and axonal transport; breakdowns in RNA processing; the potential role of environmental factors; and the confounding effects of neuroinflammation. The book is ideal for use in teaching at the advanced undergraduate and graduate levels, and serves as a comprehensive reference for a broad audience of students and researchers in neuroscience, molecular biology, biological physics and biomedical engineering.